Colonic Expression of Genes Encoding Inflammatory Mediators and Gelatinases DuringCampylobacter JejuniInfection of Conventional Infant Mice

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Colonic Expression of Genes Encoding Inflammatory Mediators and Gelatinases During Campylobacter Jejuni Infection of Conventional Infant Mice

Within 1 week following peroral Campylobacter jejuni infection, infant mice develop acute enteritis resolving thereafter. We here assessed colonic expression profiles of mediators belonging to the IL-23/IL-22/IL-18 axis and of matrix-degrading gelatinases MMP-2 and MMP-9 at day 6 post C. jejuni strain 81-176 infection. Whereas the pathogen readily colonized the intestines of infant IL-18(-/-) m...

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ژورنال

عنوان ژورنال: European Journal of Microbiology and Immunology

سال: 2016

ISSN: 2062-509X,2062-8633

DOI: 10.1556/1886.2016.00009